Intended use: For the quantitative determination of von Willebrand Factor Activity (VWF Activity) in human citrated plasma on IL Coagulation systems.
Principle: Latex particle-enhanced immunoturbidimetric assay. The activity of VWF is determined by measuring the increase of turbidity produced by the agglutination of the latex reagent. A specific ant-VWF monoclonal antibody adsorbed onto the latex reagent, directed against the platelet binding site of VWF (Glycoprotein Ib receptor), reacts with the VWF of patient plasma. The degree of agglutination is directly proportional to the activity of VWF in the sample and is determined by measuring the decrease of transmitted light caused by the aggregates.
Vials and volumes:
- 2 x 4.5 mL Latex Reagent (lyo)
- 2 x 4.5 mL Buffer (liq)
*ACL, ACL TOP, and HemosIL are trademarks of Instrumentation Laboratory.