HemosIL* Factor XIII Antigen Kit

Intended Use: Automated latex enhanced immunoassay for the quantitative determination of Factor XIII Antigen (FXIII Ag) in human citrated plasma on IL Coagulation Systems.

Principle: Factor XIII, also called fibrin-stabilizing factor, is a zymogen composed of two potentially active A subunits and two B subunits (carrier protein) that circulates in plasma as a tetramer. In the terminal phase of the clotting cascade, by the action of thrombin and Ca²⁺, the A subunits dissociate from the B subunits assuming an enzymatically active configuration. FXIII is essential for maintaining hemostasis due to its role in fibrin stabilization and in the protection of fibrin from proteolytic degradation by the fibrinolytic system.

Vials and Volumes:

• 2 vials x 2.5 mL of a suspension of polystyrene latex particles coated with a rabbit polyclonal antibody directed against the A-subunit of FXIII containing buffer, stabilizer and preservative (latex reagent)
  
• 2 vials x 5 mL of TRIS buffer containing bovine serum albumin, stabilizers and preservative (buffer)
  
• 2 vials x 6 mL of TRIS buffer containing bovine serum albumin, stabilizers and preservative (diluent)
  

*ACL, ACL TOP, and HemosIL are trademarks of Instrumentation Laboratory.

Quantity: