CD10

Part Number: A46527

The CD10 antigen is refered to as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). It is a type II integral membrane protein of 100 kDa, identified as the human membrane-associated neutral endopeptidase (EC3.4.24.11). It is expressed on uncommitted lymphoid precursors. CD10 expression is lost as cells enter the T lineage. In the B lineage, CD10 expression is lost later in ontogeny, as cells acquire surface Ig expression. It is also expressed on activated and proliferating B cells in the germinal center, and on neutrophils as well as on bone marrow stromal cells. It is also expressed on a number of other cells of epithelial origin.

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• Specifications

Specifications

UNSPSC:	41116015
Clonality:	Monoclonal
Clone:	ALB1
Form:	PC7
Format:	Liquid
Flow Product Line:	IOTest®
Flow Product Type:	Human CD Antibodies
Isotype:	IgG1 Mouse
Optimized For:	FCM
Regulatory Status:	ASR
Size(tests/volume):	100 tests
Target Species:	human

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REGULATORY STATUS

All listed products have a regulatory status as follows:

	IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
	ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
	CE: CE-marked products. CE-marked products are labeled for in vitro diagnostic use and can be traded throughout the EU.
	RUO: Research Use Only Reagents. These reagents are labeled "For Research Use Only. Not for use in diagnostic procedures."
	LUO: Laboratory Use Only Reagents. These reagents are labeled "For Laboratory Use Only."
	IVD & CE: In Vitro Diagnostic Products and CE-Marked Products. These reagents comply with the IVD and CE classifications and are distributed worldwide for in vitro diagnostic use.
	ASR & RUO: Analyte Specific Reagents & Research Use Only Reagents. These reagents are labeled ASR for distribution throughout the Americas and RUO throughout the rest of the world. These products comply with the ASR and RUO definitions above.