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  Access® Ostase®

 
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There is new hope for managing osteoporosis. A laboratory blood test, called Ostase, which can accurately measure how well bone is responding to hormone replacement therapy. The test measures the amount of a specific bone alkaline phosphatase (BAP) in the blood and gives doctors a clear indication of whether the therapy is successful in reducing bone loss. It is the only blood test available in the U.S. to aid in the management of postmenopausal osteoporosis.

Traditional Ostase helps document the success of therapy after only six months. Bone mineral density tests, on the other hand, require a minimum of twelve to twenty-four months on therapy to detect changes in bone. With Ostase, you can see accurate, measurable results in less than half the time required of bone mineral density testing.

 
Features
 
  • Quantitative measurement of bone-specific alkaline phosphatase (BAP), a biochemical marker of bone metabolism, in human serum and plasma
  • Time to first result: 30 minutes
  • Calibration stability: 42 days
  • Analytical senstivity: 0.1 µg/L
  • Broad dynamic range: 0.1 - 120 µg/L
  • Correlation with the Hybritech® Tandem® -R Ostase:
    Access Ostase = 0.9985 x Tandem -R Ostase - 0.1135 (n=411; r=0.9823)

 
More Information
 

 

 
Characteristics
 

Sample Type/Size

Serum or plasma / 25 µL

Time to 1st Result

30 minutes

Analytical Sensitivity

0.1 µg/L

Calibrator Levels

0, 7, 15, 30, 60 and 120 µg/L

Expected Range

See insert

Open Pack Stability

28 days

Calibration Stability

42 days

Protection

< 6.5 % CV

 

 
Ordering Information
 
Name Description Part Type Part Number
Access Ostase  2 packs of 50 tests/pack  Reagent  37300 
Access Ostase Calibrator  6 vials of 2.5 mL/vial  Calibrator  37305 
Access Ostase QC  2 levels, 1 vial/level of 4 mL/vial  QC (Quality Control)  37309 
 

 

*Overgaard K et al.; Clin Chem 1996; 42:973;


 
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