The Role of Automation and Robotics in High Throughput ADME Profiling of Potential Drug Candidates (Cytochrome P450 Analysis on a Core System)
K. M. Jenkins Ph.D., R. Angeles, M. T. Quintos, M. Wright,
R. A. Rourick, and D. B. Kassell
DuPont Pharmaceuticals Research Laboratories
DuPont Pharmaceuticals - www.dupont.com
Due to the highly flexible nature of the SAGIAN™ Core system it is not practical to list all the hardware requirements and their configurations. Therefore this list is provided as a starting point only. Please Contact Us for any assistance needed in designing a CORE system.
There are four basic requirements for a Core system. They are the liquid handling, transportation, software, and additional devices.
Liquid Handling Options
| Source | Part No. | Quantity | Description |
| Beckman Coulter, Inc. | 717001 | 1 | Optional Biomek® FX Single Arm System |
| Beckman Coulter, Inc. | 717004 | 1 | Optional Biomek FX Dual Arm System (multichannel pipettors) |
| Beckman Coulter, Inc. | 717007 | 1 | Optional Biomek FX Single Arm System with Span-8 pipettor |
| Beckman Coulter, Inc. | 717013 | 1 | Optional Biomek FX Dual Arm System with Span 8 pipettor |
| Beckman Coulter, Inc. | 609000 | 1 | Biomek 2000 |
| Beckman Coulter, Inc. | 609047 | 1 | Biomek 2000 Right Side Module |
| Beckman Coulter, Inc. | 609048 | 1 | Biomek 2000 Left Side Module |
Transport Options
| Source | Part No. | Quantity | Description |
| Beckman Coulter, Inc. | 148287 | 1 | 1-Meter ORCA® System |
| Beckman Coulter, Inc. | 148288 | 1 | 2-Meter ORCA System |
| Beckman Coulter, Inc. | 148289 | 1 | 3-Meter ORCA System |
Software Options
| Source | Part No. |
Quantity | Description |
| Beckman Coulter, Inc. | 719349 | 1 | Biomek FX System Software |
| Beckman Coulter, Inc. | 609983 | 1 | Biomek 2000 BioWorks™ Software |
| Beckman Coulter, Inc. | 148015 | 1 | ORCA NT Software |
| Beckman Coulter, Inc. | 147500 | 1 | SAMI® NT Core System Software |
Devices
Contact Us for a list of Core compliant devices.
* All trademarks are the property of their respective owners. Where applicable, the PCR process is covered by patents owned by Roche Molecular Systems, Inc., and F. Hoffman-LaRoche, Ltd.
