HematoFlow Technology with CytoDiff
How CytoDiff Implementation Can Reduce Your Manual Review Rate to 5%
Before CytoDiff* implementation, all samples with flags for WBC abnormalities undergo manual review. Download the PDF to see how, after CytoDiff* implementation, 95% of samples can be analyzed with an automated system (see Figure 1).
Selected Examples of CytoDiff Data Compared to Cell Images
How HematoFlow with CytoDiff Delivers Better Reviews Faster
- Enhanced clinical utility. The automated 10-part differential provides far greater insights than those available from a traditional complete blood cell count
- Improved sensitivity and statistical accuracy. HematoFlow with CytoDiff analyzes a much larger number of cells—20,000 vs. 100 to 200 in a manual slide review—making it ideal for low white blood cell populations
- Improved standardization. Increased precision eliminates technician-to-technician variability within the laboratory and enables reproducible charts and graphs
- Significantly reduced manual review rates. Laboratories can reduce the need for manual review by up to eight times, eliminating unnecessary slide making, staining, drying and microscopic examination1-6
- Simplified usage. HematoFlow with CytoDiff analysis can be learned in two to three days, without previous experience in flow cytometry, versus years of practice required for effective microscopic review
Bibliography for CytoDiff References
2Jo, Yongjun et al. “Reliable, accurate determination of the leukocyte differential of leukopenic samples by using Hematoflow method.” Korean Journal of Laboratory Medicine, 2011 July;31(3):131-137.
3Gac, F. et al. “Evaluation of CytoDiff™ on cord blood WBC differential.” International Journal of Laboratory Hematology, 2013;35(1):46-54.
4Kim, Ah Hyun et al. “White Blood Cell Differential Counts in Severely Leukopenic Samples: A Comparative Analysis of Different Solutions Available in Modern Laboratory Hematology.” Blood Research, 2014;49(2):120-126.
5Allou, Kaoutar et al. “The routine leukocyte differential flow cytometry HematoFlow™ method: A new flagging system for automatic validation.” Cytometry Part B, Clinical Cytometry, 2015;88(6):375-84.
6Kahng, Jimin et al. “Flow Cytometric White Blood Cell Differential Using CytoDiff Is Excellent for Counting Blasts.” Annals of Laboratory Medicine, 2015;35(1):28-34.
*HematoFlow and CytoDiff are not available for sale in the U.S.