Offered as part of a routine CBC with differential test, the hematology-based solution is intended to alert emergency department clinicians to sepsis or the possibility of sepsis earlier than any other indicator
Sepsis is a global healthcare crisis, affecting 26 million people worldwide every year1 and increasing at a rate of 1.5% annually.2 Sepsis not only significantly affects patients and their loved ones, but also it places considerable clinical and economic burden on the healthcare system at large.3 The availability of timely, accurate detection solutions in the emergency department where treatment can be initiated, is critical to stopping the progression of this life-threatening condition. Patients with less severe sepsis can progress to severe sepsis or septic shock within 72 hours,4 and up to half of patients with sepsis die.2,5 A clear link exists between the timeliness of treatment and mortality.6
“We want to give clinicians in the emergency department a simple tool to help them identify sepsis quickly, shortening time to treatment for these critical patients,” said Peter Soltani, Ph.D., senior vice president and general manager of the hematology business at Beckman Coulter. “Getting actionable clinical information to emergency department physicians sooner can speed critical treatment decisions.”
The Early Sepsis Indicator uses the DxH 900 hematology analyzer’s enhanced Coulter technology, which offers near native-state cellular characterization. The company’s powerful VCS 360 technology can uniquely detect morphological changes in monocytes, cells that play a role in the dysregulated immune response to sepsis. Identifying these monocyte morphological changes provides insight into possible sepsis earlier than other indicators.