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Why Do Physicians Measure C-Peptide Levels?

The bodies of people with type 1 and type 2 diabetes work differently. Type 1 diabetes occurs when the cells in the pancreas no longer produce insulin. Type 2 diabetes occurs when a person's body has developed insulin resistance. Physicians consider C-peptide levels to be the most suitable measurement for assessing endogenous insulin secretion in people with diabetes.

What Do the Test Results Mean?

C-peptide and insulin are released from the pancreas at the same time, in roughly equivalent amounts. An accurate C-peptide measurement provides a quantitative assessment of the ability of pancreatic beta cells to secrete insulin.1

Therefore, knowing these levels is crucial in understanding what type of diabetes a patient has.2

How Can the Access C-Peptide Assay Help Support Patient Care and Improve Your Lab’s Efficiency?

  • Deliver accurate results with each blood sample. The lowest LOQ with cutoffs for patients with risk factors for severe complications such as nephropathy, neuropathy, foot ulcers and retinopathy helps deliver accurate results for all patient types3
  • Avoid potential errors. The lowest cross-reactivity of proinsulin—just 3%-minimizes false elevations3
  • Streamline diabetes testing. You can run this assay on any Beckman Coulter immunoassay analyzer. This gives you the ability to run assays for insulin levels, insulin production and insulin sensitivity on the same system, to improve efficiency

Standardization WHO 13/146
LoD ≤ 0.01 ng/mL
LoQ ≤ 0.03 ng/mL
Time to First Result 40 minutes
Calibration Stability 63 days

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Comprehensive Diabetes Testing

Identification and monitoring begin with accurate testing. Laboratories need an easy-to-use comprehensive menu of diabetes chemistry assays that is simple to install, operate and integrate with existing testing workflows.

1Jones, A. G., & Hattersley, A. T. (2013). The clinical utility of C-peptide measurement in the care of patients with diabetes. Diabetic medicine: a journal of the British Diabetic Association, 30(7), 803–817. doi:10.1111/dme.12159.

2C-peptide Is the Appropriate Outcome Measure for Type 1 Diabetes Clinical Trials to Preserve β-Cell Function. Diabetes [Internet]. [cited 2018 Jul 25].

3W. M. Kuhtreiber, et al. Diabet Med. Low levels of C-peptide have clinical significance for established Type 1 diabetes,October 15; 32(10): 1346–1353. doi:10.1111/dme.12850.

Please note these items are manufactured in China.