Monocyte Distribution Width (MDW) for Early Sepsis Detection in Emergency Department: From St. Louis To Ile-Saint-Louis

Sepsis in the emergency department

MDW: Early Identification of Sepsis in the Emergency Department

Sepsis is a prevalent, deadly, yet often elusive condition in emergency departments worldwide. Despite growing recognition in significance of timely identification and guidelines-defined interventions for improvement of patients’ outcomes, diagnosing sepsis in large group of patients who present with mild and non-specific initial symptoms challenges both clinical gestalt and institutional protocols. The decades-long quest for definitive sepsis biomarkers remains largely unfulfilled and utilization of biomarkers varies widely across countries and institutions.

In this webinar recording from the ACEP20 conference, organized by the American College of Emergency Physicians, two world-recognized emergency medicine experts in sepsis, Dr. Tiffany Osborn from Washington University, St. Louis, MO and Dr. Pierre Hausfater from Sorbonne University, Paris, France will introduce and discuss a novel hematologic parameter, Monocyte Distribution Width (MDW), recently cleared by the FDA and European Authorities for sepsis detection in the Emergency Department. MDW is available as a part of CBC with Differential test which is already routinely utilized as an early screening test for a variety of the conditions. They will discuss:

  • The current state of clinical evidence for MDW derived from the series of multicenter studies
  • The practical implications of these results to the U.S. and European standards of sepsis care

Presenter: Tiffany Osborn, MD, MPH

Tiffany Osborn, MD, MPH, is triple boarded in emergency medicine, U.S. critical care and European critical care. Dr. Osborn works in the Surgical/Trauma Intensive Care Unit and Emergency Department at Washington University School of Medicine in St. Louis, MO. Dr. Osborn also serves on the National Quality Forum Sepsis Technical Expert Panel, the American College of Emergency Physicians (ACEP) TEP for the Clinical Emergency Data Registry(CEDR) and the Emergency Quality (E-QUAL) Network Sepsis Initiative.

Presenter: Professor Pierre Hausfater, MD, PhD

Professor Hausfater started his career as an internal medicine specialist focused on autoimmune and inflammatory diseases. As his career unfolded, professor Hausfater ultimately transitioned into emergency medicine in 1999. Currently, professor Hausfater is head of the emergency department at Pitie-Salpetriere hospital in Paris, France. He also oversees the coordination of emergency medicine specialists serving the healthcare needs of French residents in Paris.