Novel Sepsis Marker For Early Sepsis Detection


Hosted by the Compass Group, hear Dr. Elliott Crouser from Ohio State University review sepsis epidemiology, definitions and implications and introduce a novel sepsis biomarker, Monocytes Distribution Width (MDW). Additionally, hear Nan West, MT (ASCP) from Truman Medical Center share a septic patient case study of diagnostic challenges and explain the role of MDW.

In this on-demand webinar, Dr. Crouser discusses sepsis epidemiology, definitions and implications of sepsis. He introduces MDW sepsis biomarker which is intended to aid in early detection of sepsis in adult patients in the Emergency Department. MDW is available automatically as a part of the most common triage test - CBC with Differential. MDW may be of highest utility in patients with low initial clinical suspicion and high diagnostic uncertainty for sepsis. Additionally Nan West shares a patient case study of diagnostic challenges and the importance of early identification of sepsis.

Throughout the webinar the presenters:

  1. Discuss the current state of sepsis identification in the U.S.; approaches, outcomes, and opportunities
  2. Review the novel sepsis biomarker for the emergency department MDW—available automatically as a part of CBC with differential test
  3. Explain role of MDW for early sepsis detection while reviewing a patient case study
  4. Describe the implementation of MDW in the clinical laboratory


Elliott Crouser, M.D., from Ohio State University

Dr. Elliott Crouser is a professor of pulmonary critical care and sleep medicine at the Ohio State University Wexner Medical Center. Dr. Crouser is the author of over 80 peer-reviewed papers. His academic interests include sepsis, sarcoidosis and mitochondrial biology. Over the last five years, Dr. Crouser led the pioneering research in the role of Monocyte Distribution Width / MDW in the early detection of sepsis in Emergency Department patients. He was a principal investigator in the recently concluded 2,158-patient pivotal study for MDW.

Nan West, MT (ASCP) from Truman Medical Center

Nan West is director of laboratory operations at Truman Medical Center with oversight of Truman Health Science District and Truman laboratories and is also a medical laboratory director for Truman MLS program with her first class starting June 2020. She's been a registered medical laboratory scientist for over 35 years with clinical experience in all areas of the clinical laboratory. Both laboratories are full-service clinical laboratories, 24/7 operation with over 105 employees. The laboratory was the first in the world to go live with the Beckman Coulter Early Sepsis Indicator software and MDW biomarker.