Early Sepsis Indicator Biomarker

First FDA-cleared hematology sepsis biomarker

Help identify adult patients in the emergency department (ED) who have sepsis or are at increased risk of developing sepsis with the exclusive Early Sepsis Indicator (ESId). The only FDA-cleared hematology biomarker for sepsis, ESId measures monocyte distribution width (MDW) to support prompt clinical decision making for this often-deadly condition. This sepsis parameter is available as part of a routine CBC with differential, enabling automatic reporting without added workload burden.


Video Advanced Technology Gives Early Insights Into Sepsis

The Early Sepsis Indicator biomarker, available with the DxH 900 hematology analyzer, uses proprietary VCS 360 technology to characterize cells—including monocytes—in their near-native states. Monocytes play a key role in the dysregulated immune response in sepsis. Identifying morphological changes in monocytes provides insight into possible sepsis earlier than other indicators.

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Patient evaluation

Article Monocyte Distribution Width Adds Value to Sepsis Detection

Learn about a clinical study evaluating the diagnostic accuracy of monocyte distribution width for early sepsis detection.

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Bacteria floating in red cells in the bloodstream

Webinar Sepsis Overview: Challenges and Solutions for Laboratories

Learn about the clinical sepsis global healthcare crisis. Discover the challenges to early identification, and the role of the laboratory to understand the sepsis markers used for detection and monitoring.

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REMISOL Advance is a trademark or registered trademark of Normand-Info SAS in the United States and other countries. Used under license.