Early Sepsis Indicator Biomarker

First FDA-cleared hematology sepsis biomarker

Help identify adult patients in the emergency department who have sepsis or are at increased risk of developing sepsis with the exclusive Early Sepsis Indicator. The only FDA-cleared hematology biomarker for sepsis, Early Sepsis Indicator measures monocyte distribution width (MDW) to support prompt clinical decision making for this often-deadly condition. This sepsis parameter is available as part of a routine CBC with differential, enabling automatic reporting without added workload burden.

This product may not be available in your country or region at this time. Please contact your Beckman Coulter sales representative or distributor for more information.

Video Advanced Technology Gives Early Insights Into Sepsis

The Early Sepsis Indicator biomarker, available with the DxH 900 hematology analyzer, uses proprietary VCS 360 technology to characterize cells—including monocytes—in their near-native states. Monocytes play a key role in the dysregulated immune response in sepsis. Identifying morphological changes in monocytes provides insight into possible sepsis earlier than other indicators.

Watch video
Sepsis detection in the emergency department

Blog What is Monocyte Distribution Width?

A large unmet clinical need for the early detection of sepsis exists. MDW is a novel FDA-cleared biomarker intended to meet this need.

Read blog
Emergency department physician

Peer-Reviewed Clinical Study MDW Aids Early Sepsis Detection in the Emergency Department Beyond SIRS and qSOFA

New analysis from the pivotal study shows that patients with abnormal values of MDW at presentation have increased odds of sepsis. 

Read study
Monocytes in Sepsis

Webinar The Science Behind Early Sepsis Indicator: Why Do Monocytes Matter?

Learn how monocytes contribute to the development of sepsis and discover the scientific evidence behind a new monocyte biomarker.

View on demand

REMISOL Advance is a trademark or registered trademark of Normand-Info SAS in the United States and other countries. Used under license.